5-CHLORO-2-PYRIDINECARBOXYLIC ACID

5-CHLORO-2-PYRIDINECARBOXYLIC ACID - Names and Identifiers

Name	5-Chloropyridine-2-carboxylic acid
Synonyms	5-CHLOROPICOLINIC ACID 5-chloropicolinic acid 5-CHLORO-2-PICOLINIC ACID 5-Chloro-2-pyridinecarboxylic 5-CHLOROPYRIDINE-2-CARBOXYLIC ACID 5-Chloropyridine-2-carboxylic acid 5-CHLORO-2-PYRIDINECARBOXYLIC ACID 5-CHLORO-2-PYDRIDINECARBOXYLIC ACID 2-Pyridinecarboxylic acid, 5-chloro-
CAS	86873-60-1
EINECS	217-339-7
InChI	InChI=1/C6H4ClNO2/c7-4-1-2-5(6(9)10)8-3-4/h1-3H,(H,9,10)

5-CHLORO-2-PYRIDINECARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C6H4ClNO2
Molar Mass	157.55
Density	1.470±0.06 g/cm3(Predicted)
Melting Point	166-171℃
Boling Point	310.3±22.0 °C(Predicted)
Flash Point	141.5°C
Vapor Presure	0.00026mmHg at 25°C
pKa	3.41±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.59
MDL	MFCD04114192

5-CHLORO-2-PYRIDINECARBOXYLIC ACID - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R40 - Limited evidence of a carcinogenic effect R22 - Harmful if swallowed
Safety Description	S22 - Do not breathe dust. S36 - Wear suitable protective clothing.
Hazard Note	Harmful
Hazard Class	IRRITANT

5-CHLORO-2-PYRIDINECARBOXYLIC ACID - Introduction

Acid (acid) is an organic compound with the chemical formula C6H4ClNO2.

Nature:
Acid is a white to light yellow crystalline solid with a special smell. It is soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane, but has low solubility in water. It is stable in air and decomposes at high temperatures.

Use:
Acid is an important organic intermediate, which is widely used in the synthesis of other organic compounds. It can be used in the preparation of pesticides, drugs, dyes and coordination compounds.

Preparation Method:
Acid can be synthesized by a variety of methods, commonly used methods include the following two:
1. 2-picolinic acid chloride is reacted with chloroacetic acid to generate the target product with the aid of a catalyst and under appropriate conditions.
2. react 2-pyridyl methanol with carbonic acid chloride, and then hydrolyze with acid to obtain acid.

Safety Information:
The toxicity of acid is low, but it is still necessary to pay attention to safe operation. Avoid direct contact with skin, eyes and respiratory tract, and wear protective gloves, goggles and masks if necessary. Avoid contact with oxidizing agents and flammable substances during use and storage. Should be stored in a dry, well-ventilated place, away from fire. If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:48